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Can a daily pill slow cellular ageing? small study investigates

NCT ID NCT07659834

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily food supplement, taken for 30 days, can improve markers of cellular health in healthy adults aged 35 and over. The supplement contains ingredients thought to boost NAD+ levels and support energy production and antioxidant defenses. Researchers will measure changes in blood NAD+, other cellular markers, grip strength, and mood. The goal is to see if supplementation can support healthy ageing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Longevity supplement (Niagen NR, trans resveratrol, niacin, CoQ10, copper)
What this could lead to
If the supplement boosts NAD+ levels and other cellular health markers, it could point toward a simple way to support healthy ageing.
What could go wrong
This is a very small, early study with only 18 participants and no placebo group, so results may not be reliable or generalizable. The supplement may have no meaningful effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

18 people

The number who actually took part.

Started

Mar 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participant has provided written informed consent before participating in the study after being given a full description of the study and prior to any study-specific procedures being performed. 2. Participant has no significant medical diagnosis (health individuals) 3. Participant takes no regular prescription medication 4. Participant is not undertaking any restrictive diet (e.g. Carnivore, Low FODMAP) 5. Participant agrees to adhere to guidance on fortified food intake for the duration of the study 6. Participant is a male or non-pregnant female and is ≥35 years of age 7. If WOCBP participant is willing to adhere to one of the following methods of contraception i) Hormonal contraception e.g. the 'pill' or an implant ii) Intrauterine device (IUD) iii) Intrauterine hormone-releasing system (IUS) iv) Hysterectomy v) Vasectomised partner vi) Sexual abstinence (if it is in line with your preferred and usual lifestyle). 8. Participant can communicate well with the Investigator and to comply with the requirements for the entire study. 9. Participant has a body mass index (BMI) of 18.5 - 39.9kg/m2 (bounds included). Exclusion Criteria: 1. Participant has consumed nutritional supplement, that in the opinion of the investigator may affect any of the study primary or secondary endpoints, in the past 3 months 2. Diagnosis of any current medical condition that requires regular prescription medication or at the discretion of the investigator may affect study endpoints 3. Participated in a trial of an investigational medical product or medical device in the last 28 days. 4. Females who report to be pregnant or lactating 5. Unwilling to maintain a stable diet for the duration of the trial. 6. Unwilling to consume \<5 portions per week fortified food per week 7. History of drug or alcohol abuse 8. Alcohol use \>2 standard servings/day 9. Being in the opinion of the investigator unsuitable, in the circumstance where patient safety of scientific value of the study may be affected i.e. unable to swallow capsules, phobia to needles, significant travel that would affect adhereance study participation etc 10. Hypersensitivity to any component of the supplement 11. Previously identified niacin deficiency 12. Participant is involved in this study as an Investigator, sub-Investigator, study coordinator or other delegated study team members.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Functional Gut Clinic

    Manchester, M3 4BG, United Kingdom

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