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Are obese patients getting the right antibiotic dose before surgery?

NCT ID NCT07253805

Knowledge-focused Sponsor: Laval University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the standard doses of the antibiotic cefazolin given before bariatric surgery are high enough for obese patients. Researchers will measure drug levels in the blood and tissues of 70 patients to see if they reach the needed concentration to prevent infection. The goal is to improve dosing guidelines for this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cefazolin (an antibiotic)
What this could lead to
If successful, this could confirm or improve dosing guidelines for antibiotics in obese patients undergoing surgery, helping prevent infections more effectively.
What could go wrong
This is a small, observational study (70 people) measuring drug levels, not testing a new treatment. Results may not change practice or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Apr 2019

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All adults undergoing bariatric surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have a BMI ≥ 35 kg/m² * Undergo bariatric surgery (sleeve gastrectomy) via laparoscopy Exclusion Criteria: * Under 18 years of age * Weight over 180 kg * Penicillin allergy * Pregnant or breastfeeding women * Chronic kidney disease (eGFR \< 60 ml/min according to the Cockcroft-Gault equation) * Liver cirrhosis * Intraoperative blood loss ≥ 1 liter

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Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric sleeve gastrectomy Cefazolin

Contacts and locations

Locations

  • Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval

    Québec, Quebec, G1V 4G5, Canada

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