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Supercharged immune cells take on advanced melanoma in new trial

NCT ID NCT06961357

First seen Nov 12, 2025 · Last updated Jun 18, 2026 · Updated 27 times

Summary

This study tests a new treatment for advanced melanoma that has not responded to standard therapies. Doctors take immune cells from a patient's tumor, boost them with a molecule called CD40L, and return them to the patient after a short course of chemotherapy. The goal is to see if these enhanced cells can shrink tumors and improve outcomes. The trial enrolls 36 adults with different types of advanced melanoma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

The condition(s) this trial relates to.

acral lentiginous melanoma cutaneous melanoma iris melanoma malignant conjunctival melanoma melanoma mucosal melanoma uveal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.