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Cancer technique takes on autoimmune diseases: CAR t cells target lupus, scleroderma, and Sjogren's

NCT ID NCT06947460

Recruiting now Disease control Sponsor: Beijing GoBroad Hospital Source: ClinicalTrials.gov ↗

First seen Mar 08, 2026 · Last updated May 20, 2026 · Updated 7 times

Summary

This study tests a new treatment using a patient's own immune cells, modified to attack harmful cells in three severe autoimmune diseases: lupus kidney disease, scleroderma, and Sjogren's syndrome with lung complications. About 45 adults will receive a single infusion of CD19-BCMA CAR T cells. The main goal is to check safety within the first month, but researchers will also watch for disease improvement up to 2 years. This is not a cure; patients may still need ongoing care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 北京高博医院

    RECRUITING

    Beijing, China,Beijing, 102200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

PRIMARY SJOGREN'S SYNDROME COMBINED WITH PULMONARY HYPERTENSION REFRACTORY LUPUS NEPHRITIS SYSTEMIC SCLEROSIS SYSTEMIC SCLEROSIS