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Which therapy works best for depression? new study pits CBT against EFT

NCT ID NCT04690946

Symptom relief Sponsor: Institutt for Psykologisk Radgivning Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two common talk therapies—Cognitive Behavioral Therapy (CBT) and Emotion-Focused Therapy (EFT)—for treating depression. 112 adults with moderate or major depression received 14-18 sessions of one therapy. Researchers measured symptom changes and explored why treatments succeed or fail. The goal is to provide clearer guidance on which therapy works best and for whom.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cognitive Behavioral Therapy and Emotion-Focused Therapy
What this could lead to
If successful, this could help doctors choose the best talk therapy for depression and improve treatment outcomes.
What could go wrong
This is a completed study with 112 participants, so results are limited. It may not apply to everyone with depression, and individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

112 people

The number who actually took part.

Started

Jan 2021

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Moderate or major depressive episode as primary diagnosis Exclusion Criteria: * Serious mental illness (schizophrenia, severe bipolar disorder, recent or current psychotic episode) or intellectual disability. * Severe alcohol or drug abuse, last 12 months. * Suicidality last 6 months * Severe medical issues * If the participant is on antidepressive medication, the dosage must have been stable for more than 4 weeks, and the participant must consent to staying on the same dosage for the duration of the treatment. * The participant is currently in another treatment for depression

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression

Contacts and locations

Locations

  • Institutt for Psykologisk rådgivning

    Bergen, Bergen, 5012, Norway

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Other studies related to the condition(s) this trial covers.