New drug cocktail targets Hard-to-Treat myeloma
NCT ID NCT03798678
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 33 times
Summary
This early-phase trial tests a new drug (CB-839 HCl) combined with two standard treatments (carfilzomib and dexamethasone) in 36 adults whose multiple myeloma has come back or stopped responding to prior therapy. The main goal is to find the safest dose and check for side effects. The approach aims to block a key enzyme cancer cells need to grow, potentially making the standard drugs work better.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
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