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Eye drops or full sleep? study tests best anesthesia for cataract surgery pain

NCT ID NCT07287683

Symptom relief Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to manage pain during cataract surgery: numbing eye drops (topical anesthesia) versus general anesthesia (being fully asleep). Researchers will follow 50 adults for up to six weeks after surgery, measuring pain, complications, and satisfaction. The goal is to find out which method leads to less pain and a better recovery experience.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
topical anaesthetic (eye drops) vs general anaesthetic (drugs given intravenously or by inhalation)
What this could lead to
If this trial shows that topical anaesthesia provides similar or better pain control, it could support using simpler, less invasive anesthesia for cataract surgery.
What could go wrong
This is a small, early-phase study with only 50 participants, so results may not apply to everyone. Pain is subjective and hard to compare perfectly between groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

50 people

The number who actually took part.

Started

Apr 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Patients with unilateral cataract planned for surgery under topical or general anesthesia Exclusion Criteria: * patients under 20 or over 70 years old Eye infection Patient refusal

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Conditions

The condition(s) this trial relates to.

cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract General anesthetic drug adverse reaction Topical anaesthesia

Contacts and locations

Locations

  • Faculty of Medicine

    Alexandria, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.