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500 patients to help improve cataract lens implants

NCT ID NCT01654159

Knowledge-focused Sponsor: Aston University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is observing 500 people having cataract surgery to see how well different types of artificial lens implants (monofocal, multifocal, and toric) perform. Researchers will measure vision and patient satisfaction 3-6 months after surgery. The goal is to understand what makes each lens work well and how to design better lenses in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intraocular lenses (monofocal, multifocal, toric)
What this could lead to
If successful, this study could help doctors choose better lenses for cataract patients and guide the design of improved lenses in the future.
What could go wrong
This is an observational study, not a treatment trial. It won't directly test a new cure or therapy, so results may not lead to immediate changes in patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2013

Expected to finish

Nov 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects age between 40-85 years, may be either male or female, and may be of any race (as cataracts rarely occur before the age of 40 and above 85 other ocular pathology is common). * Subjects requiring cataract surgery. * Potential for best corrected visual acuity of 6/12 or better (as visual function in these patients will be affected by ocular pathology). * Subjects with clear intraocular media other than cataract (as assessing cataract). * General physical and mental condition allowing participation in current study. * Subjects willing to participate as evidenced by signing the written informed Exclusion Criteria: * Prior surgery on the selected eye * Previous uveitis or trauma to the selected eye, anterior or posterior synechiae * Potential for best corrected visual acuity worse than 6/12 (since this may indicate other causes of ocular pathology) * Partial or total paralysis, Parkinsons syndrome, cerebrovascular accident or other condition that could impact on the results of the study * Subject over 85 years of age (ocular pathology more common in this age group) * Subjects without adequate physical and mental capacity to enable participation in the study * Subject unwilling to participate * Systemic or topical medication known to influence visual function measures

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Conditions

The condition(s) this trial relates to.

cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Birmingham Midland Eye Centre

    Birmingham, West Midlands, B18 7QH, United Kingdom

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