Tailored eye incisions may cut glasses dependence after cataract surgery
NCT ID NCT07623317
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether placing surgical cuts in specific parts of the cornea during cataract surgery can reduce astigmatism (blurry vision from an irregularly shaped cornea) and lower the need for glasses afterward. About 100 people with cataracts and astigmatism will be randomly assigned to receive either customized or standard incisions. Researchers will measure vision and glasses dependence at 3 and 12 weeks after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Visually disturbing cataract * Corneal and refractive astigmatismus more than 1 dioptre * Able and willing to undergo study procedures and measurements 3 weeks and 12 weeks after cataract surgery. Exclusion Criteria: * Declining to participate * concomitant disease that prevents detailed objective and subjective investigations (e.g. dementia, serious ocular comorbidity limiting expected postoperative visual acuity to below 20/40) * condition damaging structural integrity of cornea (surgical complications, infection, trauma, previous corneal disease)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Eye scans probe how cataract surgery shifts the vitreous gel
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- Fuchs dystrophy and cataract surgery: does the cornea behave differently?
- Kidney clues may predict eye swelling after cataract surgery in diabetes patients
- Mind over scalpel: could guided breathing replace sedatives during eye surgery?