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Life-Saving dialysis may strip essential nutrients, study warns

NCT ID NCT07467889

Knowledge-focused Sponsor: Gulhane Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 43 critically ill adults with acute kidney injury who needed continuous kidney replacement therapy (CRRT). Researchers measured how much of certain nutrients—like carnitine, vitamins, and amino acids—were removed during dialysis. The goal was to understand if this life-saving treatment might accidentally cause nutrient deficiencies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

43 people

The number who actually took part.

Started

Jan 2023

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients (aged 18-90 years) admitted to a 36-bed general Intensive Care Unit (ICU) in a tertiary education and research hospital. The population focuses on patients diagnosed with Acute Kidney Injury (AKI) Stage 2 or 3 according to the KDIGO clinical practice guidelines. Participants are selected from patients who require an evaluation for Continuous Renal Replacement Therapy (CRRT) within the first hour of their ICU admission. The cohort includes a diverse range of critically ill patients, excluding those with end-stage chronic conditions or specific comorbidities that could confound the analysis of micronutrient clearance

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-90 years * Diagnosis of AKI Stage 2 or 3 according to KDIGO * Evaluation for CRRT requirement within the first hour of ICU admission. Exclusion Criteria: * End-stage renal disease or history of chronic RRT * AKI due to dialyzable toxins,Child-Pugh C liver cirrhosis * Terminal malignancy,AKI secondary to cardiac arrest * High risk of mortality within the first 24 hours * Prior RRT for the current AKI episode,History of kidney transplantation * Prior inclusion in this study * Pregnancy or breastfeeding * Lack of informed consent from the patient or legal representative.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury (nontraumatic) Critical illness

Contacts and locations

Locations

  • Gulhane Training and Research Hospital, Intensive Care Clinic

    Ankara, keçiören, 06010, Turkey (Türkiye)

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