New program aims to ease cancer Patients' pain and depression
NCT ID NCT07183527
First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This study tests a program called CARES that provides cancer patients with integrated screening and stepped care for symptoms like pain and depression. About 1,750 adults with cancer will be randomly assigned to CARES or standard care. The goal is to see if CARES improves quality of life and reduces symptoms better than usual care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CARES (integrated screening and stepped collaborative care program)
- What this could lead to
- If successful, CARES could become a widely used program to help cancer patients feel better and manage symptoms like pain and depression.
- What could go wrong
- This is a behavioral intervention, not a drug or cure. Results depend on how well clinics adopt the program, and benefits may vary across patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,750 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of Cancer * Age 18 years or older * Read and write in English Exclusion Criteria: * Evidence of thought disorder * Evidence of delusions * Evidence of hallucinations * Evidence of suicidal ideation with a plan
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Pittsburgh Medical Center (UPMC) Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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