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Could better fitness keep your eyes healthy?

NCT ID NCT07676747

Knowledge-focused Sponsor: Sichuan Academy of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study looks at whether being more fit is linked to lower eye pressure in healthy adults. Researchers measured eye pressure and fitness in nearly 3,000 people aged 18 to 70. The goal is to see if better cardiorespiratory fitness might help protect eye health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, it could suggest that improving fitness may help manage eye pressure and reduce glaucoma risk.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to people with eye or health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,921 people

The number who actually took part.

Started

Jul 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This single-center cross-sectional study enrolled adults who underwent health check-ups, completed standardized cardiorespiratory fitness testing, and underwent ophthalmologic examinations at the Health Management Center of Sichuan Provincial People's Hospital from July 1, 2019 to December 31, 2025. After applying the predefined inclusion and exclusion criteria, 2,921 normotensive adults were included in the final analysis.

Ages

18 to 69 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-70 years; 2. Ability to complete standardized cardiorespiratory fitness testing and provide valid data; and 3. Ability to cooperate with a comprehensive ophthalmologic examination. Exclusion Criteria: 1. Any history of glaucoma or ocular hypertension, or detection of glaucoma suspect signs such as cup-to-disc ratio ≥0.7, interocular cup-to-disc ratio asymmetry \>0.2, or localized retinal nerve fiber layer defects; 2. Ocular diseases or surgical history affecting IOP measurement or optic nerve head assessment, such as corneal disease, uveitis, intraocular surgery, high myopia (spherical equivalent ≤ -6.00 D), or other optic nerve/retinal diseases; 3. Systemic diseases that could significantly interfere with IOP, optic nerve blood supply, or cardiorespiratory function, such as uncontrolled diabetes mellitus, severe cardiovascular or cerebrovascular disease, or chronic obstructive pulmonary disease; 4. Current use of topical or systemic medications known to affect IOP, including IOP-lowering eyedrops, systemic beta-blockers, or glucocorticoids; 5. Contraindications to cardiorespiratory fitness testing, such as severe musculoskeletal disorders or uncontrolled arrhythmias; 6. A documented history of hypertension, current use of antihypertensive medications, or abnormal blood pressure on a single measurement that did not normalize on re-examination (systolic blood pressure \[SBP\] ≥140 mmHg or diastolic blood pressure \[DBP\] ≥90 mmHg); and 7. Missing key study variables that precluded further analysis.

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Conditions

The condition(s) this trial relates to.

eye disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiorespiratory fitness Eye disorders

Contacts and locations

Locations

  • Sichuan Provinvial People's HSichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital（ SAMS&SPPH，Affiliated Hospital of UESTC）ospital

    Chengdu, Sichuan, 610000, China

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