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Heart scans may reveal hidden risk after stents and bypass surgery

NCT ID NCT07133984

NEW Diagnosis Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers are studying whether detailed heart MRI scans can predict serious heart problems after people with weakened heart pumps and blocked arteries have stents or bypass surgery. The trial enrolls adults with a left ventricular ejection fraction of 40% or lower and significant coronary artery disease. Participants receive cardiac magnetic resonance imaging, a non-invasive scan that pictures heart muscle, blood flow, and scar tissue. The goal is to see whether specific scan patterns, such as damaged or poorly supplied heart muscle, are linked to later heart failure, hospital readmission, or death.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cardiac magnetic resonance imaging (CMR), a non-invasive scan that uses magnetic fields and radio waves to picture the heart
What this could lead to
If the scan patterns line up with later heart problems, doctors could use cardiac MRI to flag high-risk patients after stents or bypass surgery and adjust their care earlier.
What could go wrong
This is an observational imaging study, so it can show associations but cannot prove that the scan findings cause the outcomes. The results may not apply to patients outside the specific heart-function and artery-disease criteria used here.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 230 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2024

Expected to finish

Jan 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with iLVSD and multivessel coronary artery disease (CAD) undergoing revascularization (PCI or CABG)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Men and women ≥ 18 years old 2. LVEF ≤ 40% (quantified by echo, single-photon emission computed tomography \[SPECT\], or CMR within 2 months of enrollment) 3. Prognostically important CAD: either multivessel CAD (triple vessel or double vessel CAD including left anterior descendant artery (LAD), significant coronary stenosis defined as ≥ 70% based on coronary angiography, fractional flow reserve (FFR) ≤ 0.80 or instantaneous wave-free ratio (iFR) ≤ 0.89) or left main disease (+/- other CAD) for which significant stenosis defined as \> 50% based on coronary angiography, intravascular ultrasound (IVUS) minimum luminal area \[MLA\] value ≤ 6.0 mm2 (\< 4.5 mm2 Asian descent), or equivalent optical coherence tomography (OCT) measurements. 4. Either planned CABG/PCI within 3 months or CABG/PCI within the last 9 months. Exclusion Criteria: 1. Concomitant valve disease or other condition (e.g., LV aneurysm) requiring surgical repair or replacement 2. Contraindication to CMR (i.e. magnetically activated materials), gadolinium, regadenoson/adenosine/dipyridamole 3. Active neoplasm and/or severe end-organ dysfunction with expected life expectancy less than 5 years. \-

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic left ventricle systolic dysfunction Multivessel coronary artery disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    10 sites in 6 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dedinje Cardiovascular Institute

    RECRUITING

    Belgrade, Serbia

  • Libin Cardiovascular Institute

    RECRUITING

    Calgary, Alberta, T2N 1N4, Canada

  • MU Vienna Austria

    RECRUITING

    Vienna, Austria

  • New York Presbyterian - Queens

    RECRUITING

    Flushing, New York, 11355, United States

  • NewYork-Presbyterian Brooklyn Methodist Hospital

    RECRUITING

    Brooklyn, New York, 11215, United States

  • Ruijin Hospital Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, China

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Canada

  • Universite Laval Quebec (CRIUCPQ) Canada

    RECRUITING

    Québec, Canada

  • Weill Cornell Medicine/NewYork Presbyterian Hospital

    RECRUITING

    New York, New York, 10022, United States

  • Zbigniew Religa Lower Silesian Heart Disease Centre - Medinet

    RECRUITING

    Wroclaw, Poland

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