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Could a single CAR-T infusion stop smoldering myeloma before it turns deadly?

NCT ID NCT05767359

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times

Summary

This study tests a CAR-T cell therapy called cilta-cel in 20 people with high-risk smoldering myeloma, a pre-cancer condition. The treatment uses a patient's own immune cells, modified to attack myeloma cells. The goal is to see if it is safe and can prevent or delay the disease from becoming active multiple myeloma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.