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First test of Donor-Derived 'Living Drug' for Tough-to-Treat lymphomas

NCT ID NCT03939026

Summary

This early-phase study tested the safety of a new type of cancer treatment called ALLO-501 in adults with lymphoma that has returned or not responded to standard chemotherapy. The treatment involves giving patients immune cells (CAR T-cells) from a healthy donor, not the patient themselves, after a short course of chemotherapy drugs to prepare the body. Researchers monitored 50 participants closely to understand the treatment's safety, how the cells behave in the body, and if it helps fight the cancer.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • MD Anderson

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Norton Cancer Institute

    Louisville, Kentucky, 40207, United States

  • St. Davids South Austin Medical Center

    Austin, Texas, 78704, United States

  • Stanford University

    Stanford, California, 94305, United States

Conditions

Explore the condition pages connected to this study.