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Scientists re-engineer Patients' own immune cells to hunt childhood cancers

NCT ID NCT04539366

Summary

This early-stage trial is testing a new type of cell therapy for children and young adults whose neuroblastoma or osteosarcoma has returned or not responded to standard treatments. Doctors take a patient's own immune cells (T cells), modify them in a lab to recognize a specific protein (GD2) found on these cancer cells, and then infuse them back into the patient. The main goals are to find a safe dose, see if the treatment can be reliably made, and check for early signs that it might help control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto, California, 94304, United States

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.