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Engineered immune cells take on Hard-to-Treat lymphoma

NCT ID NCT03434769

First seen Mar 02, 2026 · Last updated May 19, 2026 · Updated 11 times

Summary

This early-phase study tests whether a patient's own immune cells (T cells) can be genetically modified to recognize and attack non-Hodgkin lymphoma that has not responded to other treatments. About 31 adults with CD19-positive lymphoma will receive these 'CAR T cells' to see if the cancer shrinks or disappears. The main goals are to measure tumor response and track any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.