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New Dual-Target CAR T-Cell therapy aims to outsmart lymphoma

NCT ID NCT07188558

First seen Sep 30, 2025 · Last updated May 01, 2026 · Updated 27 times

Summary

This study tests a new treatment called ronde-cel, which uses a patient's own immune cells engineered to attack two targets on lymphoma cells. It is for people with large B-cell lymphoma that has come back or not responded to initial treatment. About 400 participants will receive either ronde-cel or another approved CAR T-cell therapy to see which works better at controlling the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AdventHealth

    NOT_YET_RECRUITING

    Orlando, Florida, 32804, United States

  • Allegheny Health Network

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Banner MD Anderson Cancer Center

    NOT_YET_RECRUITING

    Gilbert, Arizona, 85234, United States

  • Cedars-Sinai Medical Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90048, United States

  • Cleveland Clinical Taussig Cancer Center

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Corewell Health

    NOT_YET_RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Duke Cancer Institute

    NOT_YET_RECRUITING

    Durham, North Carolina, 27705, United States

  • Hackensack

    NOT_YET_RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Honor Health

    NOT_YET_RECRUITING

    Scottsdale, Arizona, 85258, United States

  • Intermountain Healthcare

    RECRUITING

    Salt Lake City, Utah, 84143, United States

  • MD Anderson Cancer Center

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • Mayo Clinic Arizona

    NOT_YET_RECRUITING

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic Florida

    NOT_YET_RECRUITING

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

  • MedStar Georgetown University Hospital

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20007, United States

  • Moffitt Cancer Center

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Northside Hospital

    ACTIVE_NOT_RECRUITING

    Atlanta, Georgia, 30342, United States

  • Northwestern

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

  • Oncology Hematology Care Clinical Trials

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45242, United States

  • Roswell Park Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Buffalo, New York, 14263, United States

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • St. David's South Austin Medical Center

    RECRUITING

    Austin, Texas, 78704, United States

  • Swedish Cancer Institute

    NOT_YET_RECRUITING

    Seattle, Washington, 98104, United States

  • Texas Transplant Institute

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Arkansas

    NOT_YET_RECRUITING

    Little Rock, Arkansas, 72205, United States

  • University of California, Irvine

    NOT_YET_RECRUITING

    Orange, California, 92868, United States

  • University of California, Los Angeles (UCLA)

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

  • University of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Cincinnati

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45267, United States

  • University of Colorado

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Iowa

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kansas Cancer Center

    NOT_YET_RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Kentucky

    NOT_YET_RECRUITING

    Lexington, Kentucky, 40536, United States

  • University of Louisville Health

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40202, United States

  • University of Nebraska Medical Center (UNMC)

    NOT_YET_RECRUITING

    Omaha, Nebraska, 68105, United States

  • University of Texas Southwestern Medical Center

    NOT_YET_RECRUITING

    Fort Worth, Texas, 76104, United States

  • Virginia Oncology Associates

    RECRUITING

    Norfolk, Virginia, 23502, United States

Conditions

Explore the condition pages connected to this study.