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Engineered immune cells target lupus in early trial

NCT ID NCT07328581

First seen Jan 10, 2026 · Last updated Jun 14, 2026 · Updated 24 times

Summary

This study tests a new treatment called BCMA-CD19-IL-15 cCAR T cells for people with severe lupus that hasn't responded to standard therapies. The treatment uses a patient's own immune cells, modified in a lab to attack lupus-causing cells. The goal is to see if it is safe and can reduce disease activity, possibly allowing patients to stop other lupus medications. The study plans to enroll 20 participants aged 16 to 70.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

autoimmune disease disease lupus nephritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.