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Engineered immune cells offer new hope for Tough-to-Treat leukemia

NCT ID NCT06447987

First seen Jan 11, 2026 · Last updated May 19, 2026 · Updated 25 times

Summary

This early-phase trial tests whether a specially engineered immune cell therapy (huCD19-CAR T cells) is safe and effective for adults with B-cell acute lymphoblastic leukemia that has returned or not responded to standard treatments. Up to 24 participants will receive their own modified T cells after mild chemotherapy. The goal is to control the disease, not cure it, as ongoing monitoring is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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