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New CAR-T therapy shows promise for Tough-to-Treat blood cancers

NCT ID NCT06014762

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 29 times

Summary

This early-stage study is testing a new type of cell therapy called P-CD19CD20-ALLO1 for people with certain B-cell cancers (like diffuse large B-cell lymphoma) that have come back or not responded to standard treatments. The therapy uses donor immune cells that are specially designed to target and kill cancer cells. The main goal is to check the safety of this treatment and find the best dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advent Health Orlando

    Orlando, Florida, 32803, United States

  • Baylor Scott & White Research Institute

    Dallas, Texas, 75204, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Loma Linda University Cancer Center

    Loma Linda, California, 92354, United States

  • NYU Grossman School of Medicine

    New York, New York, 10016, United States

  • Ochsner Clinic Foundation

    New Orleans, Louisiana, 70121, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Our Lady of the Lake Hospital

    Baton Rouge, Louisiana, 70808, United States

  • Pennsylvania State University

    Hershey, Pennsylvania, 17033, United States

  • Prisma Health - Upstate Cancer Institute

    Greenville, South Carolina, 29605, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45206, United States

  • University of Oklahoma, Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wayne State - Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.