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Engineered immune cells take on tough kidney diseases in first human test

NCT ID NCT07535138

First seen Apr 22, 2026 · Last updated Apr 29, 2026 · Updated 3 times

Summary

This early-phase study tests a new treatment for people with autoimmune kidney diseases (lupus nephritis, IgA nephropathy, or membranous nephropathy) that have not responded to standard therapies. The treatment uses specially engineered immune cells (CAR-γδ T cells) designed to target and calm the overactive immune system. The main goal is to check safety and find the right dose in 15 participants, with a follow-up of one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xijing Hospital

    Xi'an, Shaanxi, 710032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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