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New 'Double Punch' cell therapy targets tough blood cancers

NCT ID NCT07519187

First seen Apr 16, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This early-phase trial tests a new cell therapy called CAR 70-BCMA CAR-T for people with relapsed or refractory plasma cell neoplasms, a type of blood cancer. The therapy uses a patient's own immune cells, modified to attack two targets (CD70 and BCMA) on cancer cells. The study aims to check safety and find the right dose in 20 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • General Hospital of Western Theater Command of PLA

    RECRUITING

    Chengdu, Chengdu, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR 70-BCMA dual-target CAR-T cells

What this could lead to

If it works, this could offer a new treatment option for patients with hard-to-treat plasma cell cancers that have stopped responding to other therapies.

What could go wrong

This is a very early, small trial (20 people) focused on safety. The therapy may not work or could cause serious side effects. It is not a cure, and long-term benefits are unknown.

Conditions

The condition(s) this trial relates to.

AL amyloidosis plasma cell leukemia plasma cell myeloma plasma cell neoplasm plasmacytoma Recurrence refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.