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Double attack on liver tumors: chemo plus radiation shows promise in NETs

NCT ID NCT04339036

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 20 times

Summary

This study tests a combination of two treatments for people with neuroendocrine tumors (NETs) that have spread to the liver and cannot be removed by surgery. Participants receive chemotherapy pills (capecitabine and temozolomide) plus a one-time radiation treatment delivered directly to the liver via tiny beads (Y-90 radioembolization). The goal is to see if this combination can better control tumor growth in the liver compared to either treatment alone. The study enrolls about 70 adults with grade 2 or 3 NETs where at least half of the tumor burden is in the liver.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Roswell Park Comprehensive Cancer Center

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC San Diego

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.