Medical cannabis studied as supportive care for head and neck cancer patients
NCT ID NCT03431363
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether head and neck cancer patients would use medical cannabis to help with side effects during chemotherapy and radiation. 30 patients were observed to see how many signed up for and obtained medical cannabis. The goal was to understand if cannabis could be a practical part of supportive care, not to cure the cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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30 people
The number who actually took part.
- Started
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May 2018
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with head and neck cancer that meet the eligibility criteria as described.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients must have histologically confirmed squamous cell carcinoma of the head and neck region planned for definitive or adjuvant radiation therapy and are being certified for medical cannabis * Patients must receive platinum-based chemotherapy or cetuximab concurrently with radiation therapy * Patients must be certified to obtain medical marijuana as per New York State Department of Health's Medical Marijuana Program eligibility criteria and guidelines (https://www.health.ny.gov/regulations/medical\_marijuana/faq.htm) * Age \>=18 years and ECOG performance status \<=2 (Karnofsky \>=60) * Patients must be willing to use medically certified cannabis as directed after study enrollment * Patients must be able to read English, Spanish, or French fluently * Ability to understand and the willingness to sign a written informed consent document. Exclusion Criteria: * Prior diagnosis of cannabis use disorder as defined in the DSM-V * Current or prior diagnosis of a psychotic disorder as defined in the DSM-V * Current opioid use disorder on maintenance opioid therapy * Current active use of smoked cannabis or cannabis derivatives AND unwillingness to cease use of non-medically certified cannabis for the duration of study participation * History of allergic reactions attributed to compounds of similar chemical or biologic composition to cannabis derivatives * Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Montefiore Medical Center
The Bronx, New York, 10467, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a dental assistant keep cancer Patients' mouths healthier during radiation?
- Why do Non-Smokers get head and neck cancer? scientists probe tumor DNA
- Re-irradiation plus cetuximab targets head and neck tumors that return
- Sharper tumor maps: PET scans could tighten radiation beams
- Lighting up oral cancer: dye may help surgeons see tumor edges