Weed and sperm: new study investigates link in infertile men
NCT ID NCT02932527
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether cannabis use affects sperm quality in infertile men. Researchers compared sperm samples from 71 men who used cannabis and those who did not. They measured sperm DNA health and other factors to see if cannabis might be linked to fertility problems.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cannabis
- What this could lead to
- If it succeeds, this could clarify whether cannabis use harms sperm quality in infertile men, guiding fertility advice.
- What could go wrong
- This is a small, observational study (71 participants) that only looks at sperm under a microscope. It cannot prove cause and effect, and results may not apply to all men.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
71 people
The number who actually took part.
- Started
-
Aug 2017
- Finished
-
May 2021
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Male participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male Patient, * Patient age ≥ 18 years, * Infertile patient with isolated teratozoospermia or associated with asthenozoospermia and / or oligozoospermia and / or necrozoospermia, defined according to WHO recommendations (WHO guidelines, 2010) and the David amended classification (Auger et al, 2001) for teratozoospermia * Patient with normal constitutional karyotype (46, XY). * Smoking tobacco, * Drinking ≤ 20 g (2 units) / day, * Patient exposed : Cannabis user for over 3 months and consuming at least weekly (≥ 1 / week) \[questionnaire and positive blood detection of Delta-9-Tetrahydrocannabinol (THC) and / or its derivatives (11-hydroxy-THC and 11-nor-9-carboxy-THC)\]. * Unexposed : No cannabis user (questionnaire and negative blood detection of Delta-9-THC and its derivatives) matched for age (+/- 2.5 years) with exposed patients included, Exclusion Criteria: * Patient age \> 60 years * Patient with azoospermia * Patient previously exposed to gonadotoxic treatment (chemotherapy, radiotherapy, androgen therapy and other gonadotoxic treatments), * Patient with professional toxic exposure, * Patient consuming other recreational drugs, * Patient with severely impaired sperm parameters and sperm counts \<1 million,
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Teratozoospermia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Caen University Hospital
Caen, France
-
Lille University Hospital
Lille, France
-
Rouen University Hospital
Rouen, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.