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Athlete muscle pain meets cannabis: a balm that might beat the burn

NCT ID NCT07733791

Symptom relief Sponsor: Associação Pan-Americana Multidisciplinar de Endocanabinologia Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This trial tests whether adding a topical balm with a 3:1 ratio of CBD to THC to standard oral CBD oil can better relieve chronic muscle pain in athletes. Sixty amateur or professional athletes with pain lasting at least three months will be split into two groups: one taking only oral CBD oil, the other adding the balm twice daily to sore muscles. Researchers will track pain levels, sleep quality, and recovery over 90 days to see if the combination offers extra relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a topical balm containing a 3:1 ratio of cannabidiol (CBD) to tetrahydrocannabinol (THC), used alongside oral CBD oil
What this could lead to
If it works, this could offer athletes a new, non-opioid option for managing stubborn muscle pain and speeding recovery.
What could go wrong
This is a small, non-randomized observational study, so results may be influenced by bias. The balm contains THC, which could cause skin irritation or psychoactive effects in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult athletes (amateur or professional) practicing structured physical activity (minimum 3 sessions per week) for at least 6 months, with performance, competition, or high physical performance objectives, and with an established clinical diagnosis of chronic muscle pain (≥3 months duration). Participants are recruited from the clinical practice of the principal investigator in Brazil.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Predominantly articular, bone, or non-muscular pain (e.g., fractures, degenerative arthropathies) * Presence of open skin lesions, infections, or active dermatoses at the topical application site * Current use of WADA-prohibited substances that may interfere with outcome assessment * Athletes in official competition during the study period using THC-containing formulations (due to WADA in-competition prohibition) * Severe acute musculoskeletal injury (complete muscle rupture, fracture) within the last 30 days * Cognitive or technological inability to use the follow-up platform Exclusion Criteria: * Predominantly articular, bone, or non-muscular pain (e.g., fractures, degenerative arthropathies) * Presence of open skin lesions, infections, or active dermatoses at the topical application site * Current use of WADA-prohibited substances that may interfere with outcome assessment * Athletes in official competition during the study period using THC-containing formulations (due to WADA in-competition prohibition) * Severe acute musculoskeletal injury (complete muscle rupture, fracture) within the last 30 days * Cognitive or technological inability to use the follow-up platform

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic musculoskeletal pain Delayed onset muscle soreness (DOMS)

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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More trials for these conditions

Other studies related to the condition(s) this trial covers.