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New combo therapy may boost heart recovery after attack

NCT ID NCT04927949

Disease control Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 128 heart attack patients who had a procedure to open blocked arteries. Some patients received an extra blood thinner called cangrelor on top of standard ticagrelor. The goal was to see if the combination improved blood flow to the heart and reduced leftover clots. Results are not yet reported.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

128 people

The number who actually took part.

Started

Jun 2021

Finished

Mar 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient admitted for STEMI within 24 hours from symptom onset * pretreated with ticagrelor, aspirin and enoxaparin (according local protocol) * successfully treated by primary PCI of a native coronary culprit lesion * anatomy accessible to optical coherence tomography (OCT or OFDI) Exclusion Criteria: * cardiogenic shock * stent restenosis or thrombosis * use of glycoprotein IIb/IIIa inhibitors before or during PCI * known coagulation disease * high bleeding risk (thrombocytopenia \<100,000/dL, surgery \<30 days, active bleeding) * uncontrolled arterial hypertension (\>180/110 mmHg) * history of stroke (ischemic or hemorrhagic) or transient ischemic attack * known severe renal insufficiency (eGFR \<30 ml/min) * oral anticoagulation

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Conditions

The condition(s) this trial relates to.

ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ST elevation myocardial infarction

Contacts and locations

Locations

  • CAEN University Hospital

    Caen, 14000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.