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Nerve damage linked to kidney trouble in bypass patients

NCT ID NCT07254468

Knowledge-focused Sponsor: Akdeniz University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a nerve condition called cardiovascular autonomic neuropathy (CAN) affects the risk of kidney injury in people having heart bypass surgery. Researchers tracked 912 adults before, during, and after surgery to see if those with CAN had worse kidney function or other complications. The goal was to better understand these risks, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

912 people

The number who actually took part.

Started

Nov 2021

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study includes adult patients (≥18 years old) scheduled for elective isolated Coronary Artery Bypass Graft (CABG) surgery with planned extracorporeal circulation (ECC). Participants will be evaluated preoperatively for cardiovascular autonomic neuropathy (CAN) using standardized tests. Patients with chronic kidney failure, severe chronic respiratory disease, uncontrolled hypertension, or conditions preventing autonomic testing are excluded. Both male and female adults are eligible, and all participants must provide informed consent.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older Scheduled for elective isolated Coronary Artery Bypass Graft (CABG) surgery with planned extracorporeal circulation (ECC) Provide informed consent Exclusion Criteria:Emergency or revision CABG surgeries Chronic kidney failure or dialysis Severe chronic respiratory disease (COPD, asthma, chronic bronchitis) affecting test reliability Uncontrolled hypertension Use of antiarrhythmic drugs affecting heart rate-based autonomic tests Orthopedic or neurological conditions preventing standing tests \-

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Conditions

The condition(s) this trial relates to.

acute kidney injury autonomic neuropathy coronary artery disorder diabetic autonomic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury (AKI) Cardiovascular autonomic neuropathy (CAN) Coronary artery bypass graft (CABG) Postoperative outcomes

Contacts and locations

Locations

  • Akdeniz University, Faculty of Medicine, Department of Anesthesiology and Reanimation

    Antalya, Antalya, 07050, Turkey (Türkiye)

More trials for these conditions

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