Could a simple breakfast replace the glucose drink for diabetes testing?
NCT ID NCT05789251
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial explores whether a standardized breakfast and a continuous glucose monitor can replace the traditional glucose drink test for diagnosing diabetes and prediabetes in people with Dunnigan's lipodystrophy, a rare genetic condition that causes severe insulin resistance. The study will compare the breakfast test and sensor readings against the standard oral glucose tolerance test to see if they agree. If they do, it could offer a more comfortable and practical way to monitor these patients, potentially improving adherence to regular check-ups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Standardized breakfast and continuous interstitial glucose monitoring
- What this could lead to
- If successful, this could offer a more acceptable alternative to the standard glucose drink for diagnosing diabetes in people with Dunnigan's lipodystrophy, improving follow-up and early detection.
- What could go wrong
- This is a small, early-stage study. The breakfast may not match the glucose drink's accuracy, and continuous monitoring might not align perfectly with standard tests. Results may not apply to other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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54 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject with Dunnigan's partial familial lipodystrophy followed at Reunion University Hospital not known to be diabetic. Aged 18 to 75 Having given their informed consent. Exclusion Criteria: * Diabetic patient Patient scheduled for scan within 7 days of freestyle placement protected persons: "pregnant woman, parturient, nursing mother, person deprived of liberty by judicial or administrative decision, minor, and person subject to a measure of legal protection: guardianship or curatorship)"
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Hospitalier Universitaire de La Réunion
Saint-Denis, 97400, Reunion
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