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Immunotherapy plus chemo shows promise for tough uterine cancer

NCT ID NCT06561308

First seen Dec 11, 2025 · Last updated Jun 23, 2026 · Updated 19 times

Summary

This study is testing whether adding the immunotherapy drug camrelizumab to standard chemotherapy before surgery can help shrink advanced endometrial cancer. About 39 women with stage III or IV disease will receive the combination, then undergo surgery. The main goal is to see how many have no cancer cells left in the removed tissue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Women's hospital school of medicine zhejiang university

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Camrelizumab (a PD-1 inhibitor) combined with carboplatin and paclitaxel chemotherapy

What this could lead to

If successful, this combination could become a new standard approach to shrink advanced endometrial tumors before surgery, potentially improving long-term outcomes.

What could go wrong

This is a small, early-phase (Phase 2) trial with only 39 participants, so results may not apply broadly. The added immunotherapy also carries risks of immune-related side effects.

Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial endometrioid adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.