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New method may help tiny babies breathe without a breathing tube

NCT ID NCT04209946

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 21 times

Summary

This study looked at 180 premature babies born between 24 and 30 weeks to see if giving lung medicine (surfactant) through a thin tube instead of a breathing tube reduces the need for a breathing machine. Babies received either the new method plus caffeine or standard care (CPAP) plus caffeine. The goal was to see if fewer babies needed a breathing tube in the first 3 days of life.

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Contacts and locations

Locations

  • Loma Linda Medical Center

    Loma Linda, California, 92350, United States

  • Sharp Mary Birch Hospital for Women & Newborns

    San Diego, California, 92123, United States

  • University of California, Irvine

    Irvine, California, 92868, United States

Conditions

Explore the condition pages connected to this study.