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Caffeine timing may boost gym gains, new study suggests

NCT ID NCT07410195

Knowledge-focused Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This study looks at how taking caffeine in different ways—daily low doses, gradually increasing doses, or only on workout days—affects muscle growth and strength in 180 young men who don't normally drink caffeine or exercise with weights. Participants will follow two 4-week supervised training programs with a break in between. The goal is to find the best caffeine strategy for improving muscle and strength gains.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Feb 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male sex and age between 18 and 30 years * Daily caffeine intake \<100 mg/day * resistance-training experience ≥1 year and \<3 years * Body mass index (BMI) between 18.5-25 kg/m2 * Willingness to attend all training and testing sessions regularly * Provision of written informed consent after being fully informed about the study Exclusion Criteria: * Presence of cardiovascular, metabolic, renal, hepatic, or other serious chronic diseases * Diagnosed psychiatric disorders or severe caffeine intolerance/allergy * Use of medications affecting caffeine metabolism or muscle anabolism (e.g., beta-blockers, antidepressants, anabolic steroids) * Musculoskeletal injuries that prevent safe resistance training * Smoking or alcohol consumption at levels that could affect study outcomes * Concurrent participation in another exercise intervention study * Inability to tolerate DXA scanning or blood sampling

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Conditions

The condition(s) this trial relates to.

Hypertrophy muscular atrophy space motion sickness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adaptation Exercise performance Muscle hypotrophy Muscle strength

Contacts and locations

Locations

  • Istanbul University-Cerrahpasa, Faculty of Sport Sciences Performance Laboratory

    Istanbul, Avcilar, 34010, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.