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Dual-Target CAR T-Cell therapy shows promise in early lymphoma trial

NCT ID NCT05149391

First seen Feb 01, 2026 · Last updated Jun 15, 2026 · Updated 17 times

Summary

This early-phase study tested a new treatment called C-CAR039 in 3 people with B-cell Non-Hodgkin's lymphoma that had come back or stopped responding to standard therapy. The treatment uses a patient's own immune cells, modified to recognize and attack two markers (CD19 and CD20) on cancer cells. The main goal was to check safety and side effects, while also looking at how well the cells work in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Peking University Cancer Hospital

    Beijing, China

Conditions

The condition(s) this trial relates to.

B-cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.