Could a common anxiety drug and melatonin lift depression after brain injury?
NCT ID NCT04400266
First seen May 22, 2026 · Last updated May 22, 2026
Summary
This study tests whether a combination of buspirone (an anxiety medication) and melatonin (a sleep aid) can help with depression and thinking problems after a traumatic brain injury. Ten adults with mild or moderate brain injury who are still depressed will take the combination for several weeks. Researchers will measure mood, thinking skills, and brain scans to see if the treatment works and how it affects the brain.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02144, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital Home Base Program
RECRUITINGCharlestown, Massachusetts, 02129, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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