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Veterans' blood samples could reveal hidden health effects of burn pits

NCT ID NCT07562243

Knowledge-focused Sponsor: Creative Medical Technology Holdings Inc Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will analyze blood samples from 1,000 former U.S. service members who were exposed to open-air burn pits during deployment, comparing them to unexposed veterans. Researchers will look at genes, proteins, and immune cells to find biological markers linked to exposure. The goal is to better understand health impacts and support future research, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify biological markers that help detect or monitor health problems linked to burn pit exposure in veterans.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear markers, and results may not lead to direct health benefits for participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Dec 2031

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Former U.S. Service Members and Veterans in the United States, including individuals with prior deployment-related burn pit exposure and comparable unexposed controls. Enrollment will occur through remote screening and consent followed by approved mobile phlebotomy.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older at the time of consent * Former or current U.S. Service Member, including Active Duty, Reserve, National Guard, or Veteran status * For exposed cohort: prior deployment to a location with known burn pit operations, based on participant report and available confirmation when feasible * For control cohort: no known deployment to burn pit locations * Able and willing to provide informed consent and HIPAA authorization * Willing to complete study questionnaires and donate venous blood sample * Able to complete study procedures in English or with approved translation support * Available for one baseline visit and optional future re-contact, if applicable Exclusion Criteria: * Active serious illness or infection that, in the investigator's judgment, would compromise participation or specimen integrity * Receipt of systemic chemotherapy, immunotherapy, or radiation therapy within the past 6 months * High-dose systemic immunosuppression, defined as more than 20 mg prednisone equivalent daily for more than 14 days within the past 3 months * Pregnant or currently breast-feeding * Hemoglobin less than 10 g/dL, known bleeding disorder, or platelet count less than 100 × 10\^9/L, if known * Severe psychiatric illness or other condition that impairs ability to provide informed consent * Prisoner or institutionalized individual * Prior participation in this or a related Project PHOENIX protocol * Any other condition that, in the investigator's judgment, may increase risk or interfere with study conduct or data integrity

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Conditions

The condition(s) this trial relates to.

immune system disorder Signs and Symptoms, Respiratory

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Airborne hazard exposure Biomarkers Burn pit exposure Deployment-related toxic exposure Immune dysfunction Respiratory symptoms Veteran health

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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Other studies related to the condition(s) this trial covers.