Broccoli sprouts leave a signature in your body – scientists want to find it
NCT ID NCT04641026
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study looks at what happens inside the body after eating broccoli sprouts. Researchers will measure changes in urine, blood, and gut bacteria in 83 healthy adults. The goal is to find biological markers that show someone has eaten cruciferous vegetables, which could help improve diet research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- broccoli sprouts
- What this could lead to
- If successful, this could help researchers develop simple tests to measure whether people are eating enough vegetables, which may improve diet studies.
- What could go wrong
- This is a small, early-stage observational study in healthy adults, not a treatment trial. The findings may not apply to other groups or lead to any direct health benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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83 people
The number who actually took part.
- Started
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Feb 2021
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy men and women, 18-60 years of age * Willing to stop taking herbal and phytochemical (plant-based extract or phytochemical) supplements for 1 week prior to and during the study * Willing to stop cruciferous vegetable and probiotic supplement, food and beverage intake 1 week prior to and during the study * Willing to complete a 10-day food diary during the study * Must be able to give written informed consent Exclusion Criteria: * Body Mass Index (BMI) \<18.5 or \>30.0 kg/m2 * Tobacco use, including e-cigarettes, or smoking of any substance (e.g. cannabis) in the past three months * Pregnancy, breastfeeding, or planning to become pregnant before completing the study * Engaging in vigorous exercise more than 7 hours per week * Have a significant acute or chronic illness such as cardiovascular disease, kidney or liver disease, diabetes, thyroid disorder, or radiation or chemotherapy treatment for cancer within the past five years. * Use of medications to control cholesterol (e.g. statins, cholestyramine) or fat absorption (e.g. orlistat) * Have had bariatric surgery (e.g. gastric bypass, gastric banding, sleeve gastrectomy, etc.), other gastrointestinal procedure (e.g. cholecystectomy) or disorders (e.g. Crohn's disease, celiac disease, ulcerative colitis) * Use of oral antibiotic medication within the 6 months
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Oregon State University
Corvallis, Oregon, 97331, United States
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