New drug may offer safer treatment for dangerous virus in transplant patients

NCT ID NCT07387367

Recruiting now Disease control Sponsor: SymBio Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Feb 04, 2026 · Last updated May 25, 2026 · Updated 16 times

Summary

This study tests a new IV drug, brincidofovir, against the standard treatment cidofovir for adenovirus infection in children and adults who have had a stem cell transplant. Adenovirus can be serious in these patients because their immune system is weak. The goal is to see if the new drug works better and has fewer side effects. About 180 participants will be treated for up to 12 weeks and followed for 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

Alberta Children's Hospital University of Calgary
NOT_YET_RECRUITING

Calgary, Canada
Ann and Robert H Lurie Children's Hospital
RECRUITING

Chicago, Illinois, 60611, United States
Birmingham Women's and Children's Hospital
NOT_YET_RECRUITING

Birmingham, United Kingdom
CHU Sainte Justine Hospital
RECRUITING

Montreal, Canada
Charité University Hospital
NOT_YET_RECRUITING

Berlin, Germany
Children's Healthcare of Atlanta/Emory
NOT_YET_RECRUITING

Atlanta, Georgia, 30329, United States
Children's Hospital Colorado-Center for Cancer and Blood Disorders
NOT_YET_RECRUITING

Aurora, Colorado, 80045, United States
Children's Hospital of Philadelphia
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's National Hospital
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Cincinnati Children's Hospital
RECRUITING

Cincinnati, Ohio, 45229, United States
City of Hope
NOT_YET_RECRUITING

Duarte, California, 91010, United States
Clinica Universidad de Navarra
NOT_YET_RECRUITING

Pamplona, Spain
Cohen Children's Medical Center
RECRUITING

New Hyde Park, New York, 11042, United States
Dana-Farber Cancer Institute-Brighman and Women's
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
NOT_YET_RECRUITING

Boston, Massachusetts, 02139, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Essen University Hospital
NOT_YET_RECRUITING

Essen, Germany
Fondazione IRCCS Policlinico San Matteo
NOT_YET_RECRUITING

Pavia, Italy
Fred Hutchinson Cancer Center
NOT_YET_RECRUITING

Seattle, Washington, 98109, United States
Great Ormond Street Hospital for Children
NOT_YET_RECRUITING

London, United Kingdom
Helen Devos Children's Hospital / Michigan State University
NOT_YET_RECRUITING

Grand Rapids, Michigan, 49503, United States
Hospital Universitario La Paz
NOT_YET_RECRUITING

Madrid, Spain
Hôpital Saint-Louis
NOT_YET_RECRUITING

Paris, France
IRCCS San Raffaele Hospital
NOT_YET_RECRUITING

San Raffaele, Italy
Instituto Português de Oncologia do Porto (IPO Porto) Francisco Gentil, EPE
NOT_YET_RECRUITING

Porto, Portugal
Istituto Giannina Gaslini
NOT_YET_RECRUITING

Genova, Italy
Joseph M Sanzari Children's Hospital
NOT_YET_RECRUITING

Hackensack, New Jersey, 07601, United States
Karolinska University Hospital
NOT_YET_RECRUITING

Stockholm, Sweden
Kinderheilkunde I | Universitätsklinikum Tübingen
NOT_YET_RECRUITING

Tübingen, Germany
Leeds Teaching Hospitals NHS Trust
NOT_YET_RECRUITING

Leeds, United Kingdom
Leiden Unviversity Medical Center
NOT_YET_RECRUITING

Leiden, Netherlands
Leuven, University Hospital Gasthuisberg
NOT_YET_RECRUITING

Leuven, Belgium
Medizinische Hochschule Hannover
NOT_YET_RECRUITING

Hanover, Germany
Nationwide Children's Hospital
NOT_YET_RECRUITING

Columbus, Ohio, 43205, United States
Necker Hospital
NOT_YET_RECRUITING

Paris, France
Ospedale Pediatrico Bambino Gesu'
NOT_YET_RECRUITING

Rome, Italy
Perugia Hospital
NOT_YET_RECRUITING

Perugia, Italy
Phoenix Children's Hospital
RECRUITING

Phoenix, Arizona, 85016, United States
Princess Maxima Center & UMC Utrecht
NOT_YET_RECRUITING

Utrecht, Netherlands
Rady Children's Hospital
NOT_YET_RECRUITING

San Diego, California, 92123, United States
Robert-Debré Hospital, APHP Nord Université de Paris Cité.
NOT_YET_RECRUITING

Paris, France
Royal Manchester Children's Hospital
NOT_YET_RECRUITING

Manchester, United Kingdom
Royal Marsden Hospital
NOT_YET_RECRUITING

Sutton, United Kingdom
Seattle Children's Hospital
NOT_YET_RECRUITING

Seattle, Washington, 98105, United States
Sheffield Children's Hospital
NOT_YET_RECRUITING

Sheffield, United Kingdom
St Louis Children's Hospital - Barnes Jewish Hospital
RECRUITING

St Louis, Missouri, 63110, United States
St. Anna Kinderspital- Childrens Hospital
NOT_YET_RECRUITING

Vienna, Austria
St. Jude Children's Research Hospital
RECRUITING

Memphis, Tennessee, 38105, United States
The Hospital for Sick Children
NOT_YET_RECRUITING

Toronto, Canada
The Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital
NOT_YET_RECRUITING

Newcastle upon Tyne, United Kingdom
University Children's Hospital
NOT_YET_RECRUITING

Münster, Germany
University College London Hospitals NHS Foundation Trust
RECRUITING

London, United Kingdom
University Hospital Frankfurt, am Main
NOT_YET_RECRUITING

Frankfurt, Germany
University Medical Center Hamburg-Eppendorf (UKE)
NOT_YET_RECRUITING

Hamburg, Germany
University of California Davis
NOT_YET_RECRUITING

Sacramento, California, 95616, United States
University of Chicago
NOT_YET_RECRUITING

Chicago, Illinois, 60637, United States
University of Minnesota
NOT_YET_RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Nebraska
NOT_YET_RECRUITING

Omaha, Nebraska, 68182, United States
University of Pittsburgh Medical Center Children's Hospital
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Vall d'Hebron University Hospital
NOT_YET_RECRUITING

Barcelona, Spain
Weill Cornell Medicine
NOT_YET_RECRUITING

New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.

ADENOVIRUS INFECTIONS