Breathing training may improve walking after stroke — a trial puts it to the test
NCT ID NCT07727902
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial investigates whether a specific type of breathing exercise — functional inspiratory muscle training — can improve walking patterns in people who had a stroke more than six months ago. Sixty participants will be randomly assigned to either this new training or conventional breathing exercises, both added to standard rehabilitation. The study will measure changes in gait, exercise capacity, and quality of life over eight weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- functional inspiratory muscle training (F-IMT) using a Threshold IMT device
- What this could lead to
- If it works, this approach could offer a new, non-drug way to improve walking ability and quality of life for people recovering from a stroke.
- What could go wrong
- This is a small, early-stage trial. The training may not lead to meaningful improvements in walking, and results may not apply to all stroke survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between 55 and 65 years. * Both male and female participants. * Chronic stroke patients (\>6 months after stroke onset), including ischemic or hemorrhagic stroke confirmed by neuroimaging. * Moderate gait impairment with gait speed ranging from 0.4 to 0.8 m/s. * Ability to understand instructions and communicate sufficiently to participate in the study procedures. * Breathing spontaneously without ventilatory support. * No thoracic or abdominal surgery within the previous 6 months. * No facial palsy, or mild facial palsy without limitation of labial occlusion. * Ability to walk independently for at least 10 meters with or without an assistive device. * Willingness to participate and provide written informed consent. Exclusion Criteria: * Unstable cardiovascular disease (e.g., recent myocardial infarction, uncontrolled hypertension, decompensated heart failure). * Uncontrolled metabolic disease or poorly controlled diabetes mellitus. * Severe pulmonary disease or respiratory impairment (e.g., severe COPD, hypoxemia, chronic cough, or sputum retention). * Active malignancy. * Presence of nasal feeding tube, tracheostomy tube, or any condition preventing implementation of the study procedures. * Severe musculoskeletal disorders affecting gait performance (e.g., lower limb fracture, severe osteoarthritis, or amputation). * Significant cognitive or communication impairment preventing reliable participation. * Severe spasticity (Modified Ashworth Scale \>3) or fixed contractures. * Other neurological disorders affecting gait (e.g., Parkinson's disease, multiple sclerosis, spinal cord injury). * Severe obesity (BMI ≥35 kg/m²) that may interfere with gait assessment or exercise performance. * Previous participation in inspiratory muscle training programs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a home exercise programme help stroke survivors get moving again?
- Robots and brain scans probe how stroke survivors relearn arm skills
- Which therapy restores walking after stroke? a Head-to-Head test
- Stroke recovery from home: tele-rehab may match clinic therapy for arm function
- Can watching or hearing your muscles help you walk again after a stroke?
- Could a floating treadmill and magnetic pulses supercharge stroke recovery?