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Breathing training may improve walking after stroke — a trial puts it to the test

NCT ID NCT07727902

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates whether a specific type of breathing exercise — functional inspiratory muscle training — can improve walking patterns in people who had a stroke more than six months ago. Sixty participants will be randomly assigned to either this new training or conventional breathing exercises, both added to standard rehabilitation. The study will measure changes in gait, exercise capacity, and quality of life over eight weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
functional inspiratory muscle training (F-IMT) using a Threshold IMT device
What this could lead to
If it works, this approach could offer a new, non-drug way to improve walking ability and quality of life for people recovering from a stroke.
What could go wrong
This is a small, early-stage trial. The training may not lead to meaningful improvements in walking, and results may not apply to all stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 55 and 65 years. * Both male and female participants. * Chronic stroke patients (\>6 months after stroke onset), including ischemic or hemorrhagic stroke confirmed by neuroimaging. * Moderate gait impairment with gait speed ranging from 0.4 to 0.8 m/s. * Ability to understand instructions and communicate sufficiently to participate in the study procedures. * Breathing spontaneously without ventilatory support. * No thoracic or abdominal surgery within the previous 6 months. * No facial palsy, or mild facial palsy without limitation of labial occlusion. * Ability to walk independently for at least 10 meters with or without an assistive device. * Willingness to participate and provide written informed consent. Exclusion Criteria: * Unstable cardiovascular disease (e.g., recent myocardial infarction, uncontrolled hypertension, decompensated heart failure). * Uncontrolled metabolic disease or poorly controlled diabetes mellitus. * Severe pulmonary disease or respiratory impairment (e.g., severe COPD, hypoxemia, chronic cough, or sputum retention). * Active malignancy. * Presence of nasal feeding tube, tracheostomy tube, or any condition preventing implementation of the study procedures. * Severe musculoskeletal disorders affecting gait performance (e.g., lower limb fracture, severe osteoarthritis, or amputation). * Significant cognitive or communication impairment preventing reliable participation. * Severe spasticity (Modified Ashworth Scale \>3) or fixed contractures. * Other neurological disorders affecting gait (e.g., Parkinson's disease, multiple sclerosis, spinal cord injury). * Severe obesity (BMI ≥35 kg/m²) that may interfere with gait assessment or exercise performance. * Previous participation in inspiratory muscle training programs.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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