Nose or mouth breathing: a clue to smoother anesthesia recovery?
NCT ID NCT07759284
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study explores whether the way you breathe before surgery—through your nose or mouth—is linked to coughing when the breathing tube is removed after general anesthesia. Researchers will compare 112 patients who cough during this phase with 112 who do not, looking at breathing patterns, sleep apnea history, and other factors. The goal is to see if a simple preoperative observation could help predict and manage this common discomfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, doctors might predict and prevent coughing during anesthesia recovery, making the process smoother and more comfortable for patients.
- What could go wrong
- This is an observational study, so it can only show a connection, not prove cause and effect. The results may not apply to all patients or hospital settings.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 224 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 224 patients undergoing general anesthesia with endotracheal intubation in the operating rooms of Peking University People's Hospital will be recruited between July 20, 2026, and October 31, 2026.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing general anesthesia with endotracheal intubation; * Written informed consent obtained. Exclusion Criteria: * Patients with severe psychiatric disorders; * Deaf or mute patients who are unable to answer questions; * Patients who develop postoperative cognitive dysfunction and are consequently unable to answer questions; * Patients who withdraw from the study prematurely; * Patients who are extubated after being transferred to the recovery room or intensive care unit (i.e., extubation not performed in the operating room).
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As listed by the trial registrant
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How to take part
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The official record
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A doctor treating you
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