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Rare breast lesions under the microscope: study seeks better care

NCT ID NCT06133465

Knowledge-focused Sponsor: Istituto Oncologico Veneto IRCCS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked back at medical records of over 1,000 people with rare breast conditions called florid and pleomorphic lobular carcinoma in situ (FLCIS and PLCIS). The goal was to understand how doctors currently diagnose and treat these conditions, since there are no official guidelines. By analyzing treatments, surgeries, and outcomes, the researchers hope to create clearer recommendations for managing these cases in the future.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,063 people

The number who actually took part.

Started

Oct 2023

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with pure variant pleomorphic and/or florid lobular carcinoma in situ of the breast

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Histologic diagnosis of PLCIS and/or FLCIS of the breast on both core-biopsy and/or on final specimen histology; * Aged 18 years or older. Exclusion Criteria: * Histologic diagnosis of CLCIS; * Histologic diagnosis of LCIS (any type) associated with invasive carcinoma

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Conditions

The condition(s) this trial relates to.

lobular breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast florid lobular carcinoma in situ Pleomorphic lobular breast carcinoma in situ

Contacts and locations

Locations

  • Istituto Oncologico Veneto IRCCS

    Padova, Padova, 35168, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.