Tailored letters boost breast cancer screening in Hard-to-Reach women
NCT ID NCT07472036
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether sending a culturally and linguistically tailored reminder letter could increase breast cancer screening among women aged 50-69 who had never been screened before. About 8,000 women were split into two groups: one got the standard invitation only, the other got an extra personalized reminder. The researchers measured how many women got a mammogram within 40 days, and whether the effect was different for women with lower versus higher socioeconomic status.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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7,947 people
The number who actually took part.
- Started
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Apr 2024
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 69 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Individual-level criteria: * Aged 50-69 years * Legally registered as female in the Belgian national population registry * No history of breast cancer in the previous 10 years * No bilateral mastectomy in the previous 10 years * Invited for mammography between April and June 2024 * Classified as a non-attender, defined as (1) having received at least one previous screening invitation, and (2) never having participated in the screening program. Area-level criteria: To increase the inclusion of socioeconomically vulnerable individuals while maintaining representation from the broader screening population, participants are selected from the list of individuals invited at mammographic units located in municipalities with high deprivation scores, defined as meeting at least two of the following criteria: * Average income per capita \< EUR 20,000 * Belgian Multiple Index of Deprivation score \< 6 * Proportion of residents eligible for increased reimbursement for medical expenses \> 12%. Exclusion Criteria * Actively opted out of the screening program at the time of the study * Invited for screening in the previous year * Underwent mammographic screening in the previous year
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre for Cancer Detection (CvKO)
Bruges, Belgium
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University of Antwerp
Antwerp, 2000, Belgium
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