Massive breast cancer study aims to unlock tumor secrets
NCT ID NCT01840293
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is looking at proteins and genes in breast cancer tumors from 1,780 patients. Researchers want to understand how breast cancer progresses and why it sometimes comes back. By comparing primary and recurrent tumors, they hope to find markers that could predict disease outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better understanding of breast cancer progression and identify new markers to predict recurrence.
- What could go wrong
- This is an observational study, so it does not test a treatment. Results may not directly improve patient care or lead to immediate clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 1,780 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Feb 2013
- Expected to finish
-
Jan 2038
An estimate. End dates often move.
- Lead sponsor
-
A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All newly diagnosed breast cancer patients, recurrent and stage IV metastatic breast cancer patients.
- Ages
-
18 years and older
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients diagnosed with primary breast cancer attending hospital for the resection of their tumour tissue Or -Patients with suspected or confirmed recurrent or metastatic breast cancer (Patient has a history of a biopsy- or surgically- (i.e. pathologically) confirmed primary breast cancer) attending hospital for the resection/biopsy and/or treatment of tumour tissue Or -Patient with suspected (but not necessarily biopsy confirmed) newly diagnosed stage 4 breast cancer attending hospital for the resection/biopsy and/or treatment of their tumour tissue 2. Patients receiving neoadjuvant treatment are also eligible (if applicable) 3. Patients have to be ≥ 18 years of age 4. Patients must be able to give informed consent
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metastatic breast cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The study's own enquiry address
This study publishes an address for enquiries. See it below .
-
The places running it
4 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Email: •••••@•••••
Locations
-
Beaumont Hospital
RECRUITINGDublin, Ireland
-
Cork University Hospital
RECRUITINGCork, Ireland
-
St James's Hospital
COMPLETEDDublin, Ireland
-
St. Vincent's University Hospital
RECRUITINGDublin, Ireland
-
University Hospital Limerick
ACTIVE_NOT_RECRUITINGLimerick, Ireland
-
University Hospital Waterford
RECRUITINGWaterford, Ireland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a blood test reveal when breast cancer treatment stops working?
- New antibody aims to preserve immune checkpoint while fighting cancer
- Zapping a few growing tumors may keep breast cancer drugs working longer
- Can a Two-Drug combo outsmart resistant breast and ovarian cancers?
- Can a platform trial match the right drug combo to each tumor?
- Can a vaccine teach the immune system to fight HER2-Positive tumors?