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New study to uncover hidden nerve damage from chemotherapy

NCT ID NCT07367711

Knowledge-focused Sponsor: KU Leuven Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how chemotherapy for breast cancer affects the sense of arm position (proprioception). Researchers will compare three groups: breast cancer patients who had chemotherapy, those who had surgery only, and healthy volunteers. Using robotic tasks and video tracking, they aim to better understand nerve damage that can impact daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better ways to detect and manage chemotherapy-related nerve damage, improving quality of life for breast cancer survivors.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve symptoms, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 145 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult individuals diagnosed with breast cancer or healthy controls. One patient group having undergone only breast cancer surgery. Second patient group having undergone both breast cancer surgery and chemotherapy with taxane or platinum-based chemotherapeutic agents. A third group of sex and age-matched healthy controls. Patients will be recruited in cooperation with the department of the Multidisciplinary Breast centre of the University Hospital of Leuven.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria General (applies to all participants): * At least 18 years of age at the time of signing the informed consent form * Voluntary written informed consent of the participant has been obtained prior to any screening procedures Breast cancer surgery-only patient group: * The patient is an adult oncological person between 18 and 75 years old who has been treated for cancer * The participant has undergone breast cancer surgery but has not received any radiotherapy or chemotherapy treatment (yet). * The first session takes place between two and six weeks after breast cancer surgery. * The second session takes before any follow-up treatment for breast cancer (radiotherapy or chemotherapy). Chemotherapy group: * The patient is an adult oncological person between 18 and 75 years old who has been treated for cancer. * The participant has undergone breast cancer surgery but has not received any radiotherapy (yet). * Participant has a history of treatment with platinum- or taxane-based chemotherapeutic agents, and this treatment has been terminated no later than 6 weeks before the first session. Healthy control group: * No history of cancer or chemotherapy treatment * Sex and age-matched to patient sample Exclusion Criteria: General (applies to all participants): * Participant has a history of mental or physical disorders or neurological disease beyond those related to cancer treatments. * Participant uses any prescription or non-prescription drugs on a regular basis which, in the investigator's opinion, might confound the results of the study. * Participant is currently participating or has been involved in testing an investigational drug in another clinical study within the last 4 weeks which, in the investigator's opinion, might confound the results of the study. * Participant suffered from peripheral neuropathy prior to the chemotherapeutic treatment (Only for patients). * Participant has (a history of) a lesion in the central nervous system that is known to possibly cause neuropathic pain: e.g. spinal cord injury, infarction localized in the brainstem or thalamus, syringomyelia, multiple sclerosis, or any other disorder of the CNS that, in the investigator's opinion, may cause neuropathic pain. * If applicable: Female who is pregnant, breast-feeding or intends to become pregnant or is of child-bearing potential and not using an adequate, highly effective contraceptive

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • KU Leuven, Sport Campus Arenberg, Gebouw De Nayer

    Leuven, Vlaams-Brabant, 3000, Belgium

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