Scientists attack tough brain tumors with Double-Pronged treatment
NCT ID NCT03604978
Summary
This study is testing whether combining two immunotherapy drugs with a precise form of radiation can better control aggressive brain tumors that have returned after previous radiation. It aims to find the safest dose and see if this approach shrinks tumors in adults with recurrent high-grade meningiomas. The treatment tries to use the body's immune system to fight the cancer while precisely targeting the tumor with radiation.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032, United States
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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UCHealth University of Colorado Hospital
Aurora, Colorado, 80045, United States
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UM Sylvester Comprehensive Cancer Center at Aventura
Aventura, Florida, 33180, United States
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UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, 33146, United States
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UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, 33442, United States
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UM Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, 33176, United States
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UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, 33324, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
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University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, 66205, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.