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Can zapping the brain curb nicotine cravings in schizophrenia?

NCT ID NCT07190352

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 31 times

Summary

This study tested whether targeted magnetic pulses to a specific brain region could affect attention and nicotine cravings in people with schizophrenia or schizoaffective disorder. Fifteen smokers aged 18-65 received different types of brain stimulation (including a sham version) while researchers measured changes in brain connectivity and craving levels. The goal was to understand how brain networks relate to behavior, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcranial magnetic stimulation (TMS)

What this could lead to

If successful, this could point toward a non-drug way to improve attention and reduce nicotine cravings in people with schizophrenia.

What could go wrong

This is a very small, early-stage study with only 15 participants. It was designed to understand brain activity, not to test a treatment, so results may not lead to any practical therapy.

Conditions

The condition(s) this trial relates to.

nicotine dependence Schizophrenia schizophrenia 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.