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Brain zapping study seeks to unlock stress secrets

NCT ID NCT07406503

Knowledge-focused Sponsor: Universitair Ziekenhuis Brussel Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested whether a mild electrical current applied to the scalp (tDCS) can change how the brain handles stress and imagines future events. Sixty healthy adults underwent brain scans while receiving either real or fake stimulation. The goal was purely to learn more about the brain's stress response, not to treat any condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If successful, this could help researchers understand how brain stimulation might be used to improve stress regulation and future thinking.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. Results may not apply to real-world stress disorders, and the effects of tDCS are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Sep 2018

Finished

Oct 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women aged 18-30 years. * Right-handed, healthy volunteers. * Native Dutch speakers with normal or corrected vision. * No current or past psychiatric or neurological disorder. * MRI-compatible (no metal implants, pacemaker, etc.). * Not taking psychotropic medication. * Provided written informed consent. Exclusion Criteria: * Pregnancy. * History of epilepsy or neurosurgery. * Cardiovascular, neurological, or severe medical illness. * Claustrophobia or intolerance to MRI environment. * Tattoos or piercings that cannot be removed. * Alcohol or caffeine consumption within the restricted window before scanning. * Current use of psychoactive substances or psychotropic drugs.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy participants

Contacts and locations

Locations

  • UZ Brussel

    Brussels, Brussels Capital, 1090, Belgium

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