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Brain zapping and bedside manner: a new way to fight fear and pain?

NCT ID NCT06980090

First seen Jan 06, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study tests whether a gentle, non-invasive brain stimulation technique called tTIS can reduce negative emotions like fear and pain. It also looks at how a caregiver's positive or negative words might boost or weaken that effect. About 196 healthy adults will take part, including medical students and doctors. The goal is to understand the brain mechanisms behind expectations and emotions, not to develop an immediate treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dartmouth College, Department of Psychological and Brain Sciences

    RECRUITING

    Hanover, New Hampshire, 03755, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial temporal interference stimulation (tTIS)

What this could lead to

If successful, this could point toward new ways to manage negative emotions like fear and pain using brain stimulation combined with positive expectations.

What could go wrong

This is an early-stage study in healthy volunteers, not patients. It focuses on understanding brain mechanisms, not on developing a treatment. Results may not apply to real-world medical conditions.

Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.