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New MRI trick clears up brain scans by outsmarting your breath

NCT ID NCT07305948

Diagnosis Sponsor: Region Stockholm Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 19, 2026 · Updated 3 times

Summary

This study tests a new way to process brain MRI scans that reduces blurring caused by breathing. Researchers will compare standard images with those corrected by the new method in 100 adult patients. The goal is to see if the correction makes scans clearer for diagnosing brain diseases, without adding extra time or contrast agents.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
FID-DORK MRI correction method
What this could lead to
If successful, this could make brain MRI scans clearer and more reliable for detecting small abnormalities like bleeding or iron deposits.
What could go wrong
This is a small, early-stage study focused on image quality, not treatment. The method may not show significant improvement over standard scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Mar 2026

Finished

Aug 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be selected from adult patients referred for routine clinical brain MRI examinations at Karolinska University Hospital in Stockholm, Sweden. These individuals represent a typical clinical population undergoing MRI for a wide range of neurological indications, including tumors, vascular disorders, inflammatory conditions, and other brain diseases. Only patients scheduled for standard-of-care brain MRI that includes a susceptibility-weighted sequence (SWI) will be approached for participation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (18 years or older) * Undergoing a routine clinical brain MRI at Karolinska University Hospital * Able to understand the study information and provide written informed consent * Sequence parameters and scan protocol compatible with the research acquisition (3D-EPI SWI) Exclusion Criteria: * Patients unable to give informed consent * Standard contraindications to MRI (e.g., non-MRI safe implants, severe claustrophobia) * Clinical conditions requiring urgent imaging where research consent is not feasible * Significant motion or incomplete scans preventing creation of research images (rare)

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Conditions

The condition(s) this trial relates to.

brain disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain diseases

Contacts and locations

Locations

  • Karolinska University Hospital

    Stockholm, Solna, 171 76, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.