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Hands and mouth: brain study could unlock new stroke rehab

NCT ID NCT06908863

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study looks at how the brain controls fine hand movements and speech, using MRI scans in 20 healthy right-handed adults aged 18-35. Participants first practice motor and facial tasks for two weeks, then have an MRI while performing similar tasks. The goal is to find shared brain networks, which could one day help stroke patients recover speech through hand exercises.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward new rehabilitation strategies for stroke patients by using hand exercises to improve speech.
What could go wrong
This is a very small pilot study with only 20 healthy young adults, so results may not apply to patients or lead to direct treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Oct 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male or female between the ages of 18 and 35 2. Right-handed 3. Member of beneficiary of a social security insurance 4. Signature of an informed consent Exclusion Criteria: 1. Disorders of fine manual motor skills and/or articulatory disorders 2. A neurological history that has affected the subject's cerebral function (stroke, head injury) 3. Contraindication to MRI (presence of ferromagnetic material in the body, claustrophobia) 4. Pregnant women 5. Taking medication that may alter the cerebral haemodynamic signal

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Conditions

The condition(s) this trial relates to.

Speech

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Correlations between cerebral motor control during A manual task and during an articulatory task

Contacts and locations

Locations

  • CHU de Nice

    Nice, PACA, 06003, France